Collections / Conserved principles of spatial biology define tumor heterogeneity and immunotherapy sensitivity
Conserved principles of spatial biology define tumor heterogeneity and immunotherapy sensitivity
Spatial transcriptomics experiments were performed on human patient pre-treatment biopsies for patients with either NSCLC or DLBCL. This was part of a larger study on pan-tumor spatial biology organization.
Datasets18
Size~2.5 GB
AssayVisium
Samplehuman · multiple
KindTime course
Download the whole collection
Python · sddb client
from sddb import Catalog
cohort = Catalog().collection("geo-gse292299")
cohort.members # the 18 datasets as a table
print(cohort.licenses()) # check the terms before you download
sdatas = cohort.to_dict() # {uid: SpatialData}, cached locally
# or keep the .zarr files in a folder of your choice:
# sdatas = cohort.to_dict(dest="data/") Python · lamindb
Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.
import lamindb as ln
db = ln.DB("scverse/spatialdata-db")
coll = db.Collection.get(key="geo-gse292299")
coll.ordered_artifacts.to_dataframe() # the 18 members, ordered
# download every member .zarr to the local cache:
paths = [a.cache() for a in coll.ordered_artifacts.all()] Shell
# sddb client: download every member .zarr into data/
sddb-cli download --collection geo-gse292299 --dest data/ Licenses: 18 NCBI GEO policy
Member datasets · 18
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