Collections / 10X Visium Spatial transcriptomics of murine small intestine 6 and 14 days post Heligmosomoides polygyrus infection with or without LXR agonist GW3965

10X Visium Spatial transcriptomics of murine small intestine 6 and 14 days post Heligmosomoides polygyrus infection with or without LXR agonist GW3965

In this dataset, we investigate the murine proximal small intestine spatial transcriptomic profile at the day 6 and day 14 post Heligmosomoides polygyrus infection and compare the genes alteration with and without LXR activation by sythetic ligand GW3965 diet.

Datasets4
Size~85.0 MB
AssayVisium
Samplemouse · small intestine
KindComparison
Flag a data issue
www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE266136 ↗
Python · sddb client
from sddb import Catalog

cohort = Catalog().collection("geo-gse266136")
cohort.members        # the 4 datasets as a table

print(cohort.licenses())              # check the terms before you download

sdatas = cohort.to_dict()             # {uid: SpatialData}, cached locally
# or keep the .zarr files in a folder of your choice:
# sdatas = cohort.to_dict(dest="data/")
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
coll = db.Collection.get(key="geo-gse266136")
coll.ordered_artifacts.to_dataframe()   # the 4 members, ordered

# download every member .zarr to the local cache:
paths = [a.cache() for a in coll.ordered_artifacts.all()]
Shell
# sddb client: download every member .zarr into data/
sddb-cli download --collection geo-gse266136 --dest data/

Licenses: 4 NCBI GEO policy

Open in Vitessce
Visium
Mouse small intestine
GSM8241316
mouse small intestine 25.0 MB 3,831 spots silver H&E NCBI GEO policy
TechnologyVisium
Organismmouse
Tissuesmall intestine
Size25.0 MB
Spots3,831
Magnificationother · 3.507 µm/px
silver H&E NCBI GEO policy Open in Vitessce
Open in Vitessce
Visium
Mouse small intestine
GSM8241319
mouse small intestine 11.5 MB 3,478 spots silver H&E NCBI GEO policy
TechnologyVisium
Organismmouse
Tissuesmall intestine
Size11.5 MB
Spots3,478
silver H&E NCBI GEO policy Open in Vitessce
Open in Vitessce
Visium
Mouse small intestine
GSM8241317
mouse small intestine 34.4 MB 4,679 spots silver H&E NCBI GEO policy
TechnologyVisium
Organismmouse
Tissuesmall intestine
Size34.4 MB
Spots4,679
silver H&E NCBI GEO policy Open in Vitessce
Open in Vitessce
Visium
Mouse small intestine
GSM8241318
mouse small intestine 14.1 MB 4,346 spots silver H&E NCBI GEO policy
TechnologyVisium
Organismmouse
Tissuesmall intestine
Size14.1 MB
Spots4,346
silver H&E NCBI GEO policy Open in Vitessce

Cite this collection

No linked publication found — please cite the data source.