Collections / Orthotopic 4T1 tumors spatial transcriptomics

Orthotopic 4T1 tumors spatial transcriptomics

4T1 tumors, 4 weeks after implantation were excised and analyzed using the 10X Visium technology.

Datasets4
Size~192 MB
AssayVisium
Samplemouse · mammary gland
KindOther
Flag a data issue
PMID:40670787 ↗
Python · sddb client
from sddb import Catalog

cohort = Catalog().collection("geo-gse230098")
cohort.members        # the 4 datasets as a table

print(cohort.licenses())              # check the terms before you download

sdatas = cohort.to_dict()             # {uid: SpatialData}, cached locally
# or keep the .zarr files in a folder of your choice:
# sdatas = cohort.to_dict(dest="data/")
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
coll = db.Collection.get(key="geo-gse230098")
coll.ordered_artifacts.to_dataframe()   # the 4 members, ordered

# download every member .zarr to the local cache:
paths = [a.cache() for a in coll.ordered_artifacts.all()]
Shell
# sddb client: download every member .zarr into data/
sddb-cli download --collection geo-gse230098 --dest data/

Licenses: 4 NCBI GEO policy

Visium
Mouse mammary gland
GSM7186933
mouse mammary gland breast carcinoma 44.8 MB 4,392 spots silver H&E NCBI GEO policy
TechnologyVisium
Organismmouse
Tissuemammary gland
Conditionbreast carcinoma
Size44.8 MB
Spots4,392
silver H&E NCBI GEO policy
Open in Vitessce
Visium
Mouse mammary gland
GSM7186934
mouse mammary gland breast carcinoma 61.5 MB 4,185 spots silver H&E NCBI GEO policy
TechnologyVisium
Organismmouse
Tissuemammary gland
Conditionbreast carcinoma
Size61.5 MB
Spots4,185
silver H&E NCBI GEO policy Open in Vitessce
Open in Vitessce
Visium
Mouse mammary gland
GSM7186935
mouse mammary gland breast carcinoma 40.6 MB 3,924 spots silver H&E NCBI GEO policy
TechnologyVisium
Organismmouse
Tissuemammary gland
Conditionbreast carcinoma
Size40.6 MB
Spots3,924
silver H&E NCBI GEO policy Open in Vitessce
Open in Vitessce
Visium
Mouse mammary gland
GSM7186932
mouse mammary gland breast carcinoma 44.8 MB 3,787 spots silver H&E NCBI GEO policy
TechnologyVisium
Organismmouse
Tissuemammary gland
Conditionbreast carcinoma
Size44.8 MB
Spots3,787
silver H&E NCBI GEO policy Open in Vitessce

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