Collections / mousemodel_Heptablastoma spatial transcriptomics

mousemodel_Heptablastoma spatial transcriptomics

Lack of relevant animal models and cell lines hampers the understanding of hepatoblastoma and identification of therapeutic targets. We report a hepatoblastoma murine model that faithfully recapitulates the pathological features of mixed fetal and embryonic hepatoblastoma, with transcriptomics resembling the high-risk gene signatures of human disease

Datasets5
Size~330 MB
AssayVisium
Samplemouse · liver
KindOther
Flag a data issue
PMID:37414763 ↗
Python · sddb client
from sddb import Catalog

cohort = Catalog().collection("geo-gse195575")
cohort.members        # the 5 datasets as a table

print(cohort.licenses())              # check the terms before you download

sdatas = cohort.to_dict()             # {uid: SpatialData}, cached locally
# or keep the .zarr files in a folder of your choice:
# sdatas = cohort.to_dict(dest="data/")
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
coll = db.Collection.get(key="geo-gse195575")
coll.ordered_artifacts.to_dataframe()   # the 5 members, ordered

# download every member .zarr to the local cache:
paths = [a.cache() for a in coll.ordered_artifacts.all()]
Shell
# sddb client: download every member .zarr into data/
sddb-cli download --collection geo-gse195575 --dest data/

Licenses: 5 NCBI GEO policy

Open in Vitessce
Visium
Mouse liver
GSM7016926
mouse liver hepatoblastoma 64.9 MB 4,992 spots silver H&E NCBI GEO policy
TechnologyVisium
Organismmouse
Tissueliver
Conditionhepatoblastoma
Size64.9 MB
Spots4,992
silver H&E NCBI GEO policy Open in Vitessce
Open in Vitessce
Visium
Mouse liver
GSM7016921
mouse liver hepatoblastoma 77.0 MB 4,992 spots silver H&E NCBI GEO policy
TechnologyVisium
Organismmouse
Tissueliver
Conditionhepatoblastoma
Size77.0 MB
Spots4,992
silver H&E NCBI GEO policy Open in Vitessce
Open in Vitessce
Visium
Mouse liver
GSM7016924
mouse liver hepatoblastoma 59.9 MB 4,992 spots silver H&E NCBI GEO policy
TechnologyVisium
Organismmouse
Tissueliver
Conditionhepatoblastoma
Size59.9 MB
Spots4,992
silver H&E NCBI GEO policy Open in Vitessce
Open in Vitessce
Visium
Mouse liver
GSM7016923
mouse liver hepatoblastoma 66.0 MB 4,989 spots silver H&E NCBI GEO policy
TechnologyVisium
Organismmouse
Tissueliver
Conditionhepatoblastoma
Size66.0 MB
Spots4,989
silver H&E NCBI GEO policy Open in Vitessce
Open in Vitessce
Visium
Mouse liver
GSM7016922
mouse liver hepatoblastoma 62.5 MB 4,992 spots silver H&E NCBI GEO policy
TechnologyVisium
Organismmouse
Tissueliver
Conditionhepatoblastoma
Size62.5 MB
Spots4,992
silver H&E NCBI GEO policy Open in Vitessce

Cite this collection

No linked publication found — please cite the data source.