Collections / A novel model of binge ethanol exposure reveals enhanced neurodegeneration with advanced age

A novel model of binge ethanol exposure reveals enhanced neurodegeneration with advanced age

Datasets4
Size~3.6 GB
AssayVisium
Samplemouse · brain
KindComparison
Flag a data issue
10.1016/j.bbi.2023.12.034 ↗
Download the whole collection
Python · sddb client 
from sddb import Catalog

cohort = Catalog().collection("doi-10-1016-j-bbi-2023-12-034")
cohort.members        # the 4 datasets as a table

print(cohort.licenses())              # check the terms before you download

sdatas = cohort.to_dict()             # {uid: SpatialData}, cached locally
# or keep the .zarr files in a folder of your choice:
# sdatas = cohort.to_dict(dest="data/")
Install (Python 3.12+) Docs →
Python · lamindb

Needs pip install lamindb and network access to the Lamin database, which is limited during the alpha. If it fails, use the Client tab.

import lamindb as ln

db = ln.DB("scverse/spatialdata-db")
coll = db.Collection.get(key="doi-10.1016/j.bbi.2023.12.034")
coll.ordered_artifacts.to_dataframe()   # the 4 members, ordered

# download every member .zarr to the local cache:
paths = [a.cache() for a in coll.ordered_artifacts.all()]
Install (Python 3.12+) Docs →
Shell 
# sddb client: download every member .zarr into data/
sddb-cli download --collection doi-10-1016-j-bbi-2023-12-034 --dest data/
Install (Python 3.12+) Docs →

Licenses: 4 CC BY-NC-SA 4.0

About the study

Binge ethanol exposure in advanced age elevates neuroinflammation and early indicators of neurodegeneration and cognitive impairment in female mice.

Read the abstract at the source →
Member datasets · 4
Open in Vitessce
Visium
Mouse brain
NCBI802
mouse brain 896 MB 2,743 spots silver H&E
TechnologyVisium
Organismmouse
Tissuebrain
Size896 MB
Spots2,743
Magnification20x · 0.468 µm/px
silver H&E Open in Vitessce
Open in Vitessce
Visium
Mouse brain
NCBI801
mouse brain 895 MB 2,889 spots bronze H&E
TechnologyVisium
Organismmouse
Tissuebrain
Size895 MB
Spots2,889
Magnification20x · 0.468 µm/px
bronze H&E Open in Vitessce
Open in Vitessce
Visium
Mouse brain
NCBI799
mouse brain 886 MB 2,648 spots bronze H&E
TechnologyVisium
Organismmouse
Tissuebrain
Size886 MB
Spots2,648
Magnification20x · 0.468 µm/px
bronze H&E Open in Vitessce
Open in Vitessce
Visium
Mouse brain
NCBI800
mouse brain 897 MB 2,784 spots silver H&E
TechnologyVisium
Organismmouse
Tissuebrain
Size897 MB
Spots2,784
Magnification20x · 0.468 µm/px
silver H&E Open in Vitessce

Cite this collection

doi.org/10.1016/j.bbi.2023.12.034 ↗
BibTeX 
@article{Anton_2024,
  title = {Binge ethanol exposure in advanced age elevates neuroinflammation and early indicators of neurodegeneration and cognitive impairment in female mice},
  volume = {116},
  ISSN = {0889-1591},
  url = {http://dx.doi.org/10.1016/j.bbi.2023.12.034},
  DOI = {10.1016/j.bbi.2023.12.034},
  journal = {Brain, Behavior, and Immunity},
  publisher = {Elsevier BV},
  author = {Anton, Paige E. and Rutt, Lauren N. and Kaufman, Michael L. and Busquet, Nicolas and Kovacs, Elizabeth J. and McCullough, Rebecca L.},
  year = {2024},
  month = Feb,
  pages = {303–316}
}